Previously undescribed 6.6-kilobase R plasmid in penicillinase-producing Neisseria gonorrhoeae

Previously undescribed 6.6-kilobase R plasmid in penicillinase-producing Neisseria gonorrhoeae.

A penicillin-resistant Neisseria gonorrhoeae strain was isolated. The resistance was due to the production of TEM-1 beta-lactamase encoded by a plasmid. This 6.6-kilobase plasmid was compared with the previously known 7.4- and 5.3-kilobase penicillin R plasmids of N. gonorrhoeae.

Spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae.

Since March 1976, 7 cases of PPNG have been identified in Alaska. However, 3 of these cases occurred in 1980. We recommend that all physicians and other health care providers be alert for any patient diagnosed as having gonorrhea who gives a history of exposure in Southeast Asia or the Philippines. Such patients should be cultured, the lab slip marked "test for possible PPNG", and treatment giv...

Spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae--California.

Characterization of a novel Neisseria gonorrhoeae penicillinase-producing plasmid isolated in Australia in 2012.

Ella Trembizki, Cameron Buckley, Andrew Lawrence, Monica Lahra, David Whiley, on behalf of the GRAND Study Investigators Queensland Paediatric Infectious Diseases Laboratory, Queensland Children’s Health Services, Brisbane, Queensland, Australia; Queensland Children’s Medical Research Institute, The University of Queensland, Brisbane, Queensland, Australia; Microbiology and Infectious Diseases ...

Penicillinase-producing plasmid types in Neisseria gonorrhoeae clinical isolates from Australia.

Penicillinase-producing Neisseria gonorrhoeae (PPNG) carrying the blaTEM-135 gene is of particular concern, as it is considered a stepping stone toward resistance to extended-spectrum cephalosporins. Here, we sought to characterize plasmid types and the occurrence of the blaTEM-135 gene for N. gonorrhoeae clinical isolates from Australia. We found that blaTEM-135 was prevalent in Australian PPN...